For around 20 successful years since its discovery, Viagra has been playing an important role in the lives of many men. It has saved many relationships from breaking and many men from losing their self-confidence. Yes, erectile dysfunction is what we are talking about. It is a troublesome health condition in men whereby there is a decrease in their ability to sustain a proper erection for a physical intercourse. But with the help of this little blue pill, the fear of impotence has reduced. It is not considered as a lifelong problem anymore. Also, as you can avail Viagra online from any medical store, the treatment of this health condition has become more convenient and easy. Viagra: The First Ever Oral ED pill Viagra is a well-known erectile dysfunction medicine that is known to bring about a whopping 80% improvement in the erectile capacity of men. It belongs to a drug class called PDE5 inhibitor that increases the blood flow to the penile nerve and helps the person to obtain an erection. Its active ingredient is Sildenafil. Under its effect, one can expect to sustain an erection for 4 long hours without any hindrance. Originally, this little blue pill was discovered to treat certain other health conditions like pulmonary arterial hypertension and angina, a chest pain related to coronary heart disease. But as trials and tests were conducted, it was found that most men reported increase in the erection capacity. This led to the drug being further tested for the treatment of erectile dysfunction. As a result, in 199, the Food and Drug Administration approved the use of Viagra in the treatment of this male health condition. It became the first-ever oral ED pill for men at that point of time. What causes erectile dysfunction? Erectile dysfunction, or simply Impotence, is not simple as it sounds. This problem arises due to a number of physical and psychological health conditions as one enters the age group of 40 to 70 years. Common physical health symptoms like diabetes and high blood pressure are frequently reported causes of erectile dysfunction. Low testosterone level can also lead to reduced erectile capacity. On the other hand, psychological conditions include stress, fatigue and even depression which can cause impotence. In men suffering from erectile dysfunction, there is a presence of an enzyme called PDE5 (phosphodiesterase type 5). This enzyme can block the conversion process of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate).The cGMP is an important chemical present in the bloodstream that facilitates the smooth flow of blood. But due to its degradation, the blood vessels contract and the blood flow to the penile nerve reduces. This causes erectile dysfunction. How does Viagra work? Viagra is a basic PDE5 inhibitor that works when there is a sexual stimulation present. When there is such stimulation, nitric oxide is released. The signals come in from the endothelial cells in the penis and the GTP converts into cGMP. The active Sildenafil can bind to the PDE5 enzymes, blocking it from degrading cGMP. This ensures that the cGMP functions smoothly in dilating the blood vessels. As more of cGMP and less of PDE5 is present, the blood flows freely to the penile nerve and fills in the erectile tissue. This is how a firms and lasting erection can be obtained with the help of Viagra. Remember that, Viagra is only an erectile dysfunction medicine. It does not protect one from sexually transmitted diseases (STDs) and one should take necessary precautions for that accordingly. Viagra Dosage Guidelines:
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January 2019
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